Owens launched his fashion line in 1994, operating out of a store in Hollywood Boulevard. He moved to Paris in 2003 with his companion Michèle Lamy, whom he married in 2006, and set up his home and atelier inside a historic five-storey building that previously served as offices for former French President François Mitterrand. His runway collections have been mounted in Paris since then. In 2004, Owens and Michèle Lamy established their own fashion company Owenscorp, and described their business partnership as "asking a gypsy to organise a war with a fascist."
In July 2005, Owens introduced a furniture collection. Using raw plywood, marble, alabaster, bronze, leather, and moose antlers, the collection is inspired by his favorite shapes from Eileen Gray to Brâncuși to California skate parks. The furniture collection has since been shown at the Musée d'Art modern in Paris and the Museum of Contemporary Art, Los Angeles. Owens credits his wife, Michèle Lamy, as the creative force behind his furniture show. The exhibit showcases new works as well as classic pieces, in which some were envisioned for this newest store located in Soho, New York. The couple has worked together throughout the design process for his furniture line. Owens comes up with the drawings in which Lamy then creates the preliminary models for. Before his wife hires artisans to create the final pieces, the two carve, re-proportion, and make any adjustments beforehand. Owens leaves the installation process in Lamy's hands, who writes the summaries for the pieces as well.
In 2013, Owens exhibited his 'Prehistoric' collection at Carpenters Workshop Gallery in London. Owens' design colour palette in this seven piece collection stretches from white to black, stopping nowhere in between. "The show is entitled 'Prehistoric' – a name that reflects its inspiration, the origins of humanity, it recalls a mysterious ancient civilisation. Its aura is one of spiritual ritual, archaic ceremony and supreme power".